This course will cover both the fundamentals and applications of molecular chemistry as it relates to the properties of materials. Fundamental topics will include: (1) the design of chemical structures and their relationship to optical and electronic properties; (2) the chemistry and physics of covalent and non-covalent bonding; (3) the relationship of atomic bonding to molecular geometry and local symmetry; (4) crystal structures of extended solids; and (5) extension of these principles to electronic structure, elasticity, and vector and tensor descriptions of materials properties. Applications to diverse areas of engineering will be discussed.