Immunoengineering is the next frontier in the field of biomedical engineering (BME) where concepts from material science, synthetic biology, and engineering are used to modulate immune responses. We will focus on how interdisciplinary ideas can be used to tune both the design and delivery of therapies to stimulate, limit, or direct immune responses towards specific cellular targets or pathogens. The lecture contents will draw from textbooks and scientific journal articles to encompass theoretical principles and novel applications that will be learned through weekly assignments and collaborative discussions. The specific topics that will be covered include the development of adjuvants, antigens for B and T cell vaccines, tolerizing therapies, and immunotherapies such as adoptive cell transfer approaches.